PART 1 (10 marks) Atherosclerotic plaque formation
Rupture of a plaque in the left coronary artery
A stable adequate is blood flow and the symptoms quickly subside without any damage to the heart and dot not tend to form cloth.
A Unstable plaque is restriction of blood flow in the coronary artery,
An unstable plaque going to be hemorrhage into the plaque or thrombotic occlusion of the vessel lumen.
cluding the arteries to the heart.
PART 2 (10 marks)
Hypertension mechanisms and pathophysiology
Describe the risk factors that contribute to hypertension
• Describe how the risk factors contribute to the development of hypertension
salt intake, obesity and insulin resistance, the renin-angiotensin system, and the sympathetic nervous system.
Renin is secreted from the juxtaglomerular apparatus of the kidney in response to glomerular under perfusion or a reduced salt intake. It is also released in response to stimulation from the sympathetic nervous system